Guide to Infection Control cover

The latest 5th edition of A Guide to Infection Control in the Hospital is now available. This handy pocket-sized manual contains 60 chapters that explain key principles and guidelines for reducing the rate of nosocomial infections and practical measures intended to improve quality of care, minimize risk, save lives, and reduce costs.

In developed countries, anywhere from 5 to 10% of patients admitted to acute care hospitals acquire an infection which was not present or incubating on admission. The attack rate for developing countries can exceed 25%.

Because the illnesses, deaths, and added costs related to nosocomial infections, the field of infection control has grown in importance over the last 30 years. Although estimates vary regarding the proportion of nosocomial infections which are preventable, it may be as high as 20% in developed countries and as high as 40% or more in developing countries. Furthermore, in developed countries 5 to 10% of infections acquired in the hospital occur as part of an epidemic or cluster. The figure is larger for developing countries.

The emphasis, however, is that all nosocomial infections, clusters and outbreaks are potentially preventable, and that now, more than ever, opportunities are excellent for risk reduction interventions. At the center of this are the basic principles of good infection control.

Although our discipline, like others, is in constant evolution, this booklet contains the most up to date principles and interventions designed to reduce the rate of nosicomial infections. The chapters herein have been written by international authorities in infection control and hospital epidemiology. They are intended to improve quality of care, minimize risk, save lives, and reduce costs. As out intention is to publish and up to date guide every two years, we welcome your comments and thoughts as we proceed with future editions.

The English print version of the 5th edition of the Guide may be purchased directly through the Society. Individuals from developing countries may receive the Guide with the payment of postage, upon request by contacting ISID directly.

ISID has made a pdf version of the 5th edition of the Guide to Infection Control in the Hospital available as a free download to members. New members will recieve a personalized link to enable a download of a PDF copy of the Guide.

To contact ISID about the Guide, please send an email to

Feedback and comments from users of the Guide are welcome and encouraged.
Richard P. Wenzel, MD, MSc, Professor and Former Chairman, Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA

Gonzalo M.L. Bearman, MD, MPH, Professor of Medicine, Associate Hospital Epidemiologist, Department of Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA

Michael Stevens, MD, MPH, Assistant Professor of Medicine, Division of Infectious Diseases; Associate Hospital Epidemiologist; Director, Antimicrobial Stewardship Program; Director, Travel & Tropical Medicine Clinic, Virginia Commonwealth University Health System, Richmond, Virginia, USA

Michael Edmond, MD, MPH, MPA, Professor of Internal Medicine, Chief Quality Officer, University of Iowa, Iowa City, Iowa, USA

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Chapter 1: Importance of Infection Control

Chapter 2: Organization

Chapter 3: Role of the Microbiology Laboratory in Infection Control

Chapter 4: Antibiotic Resistance Challenges

Chapter 5: Waste Management

Chapter 6: Hand Hygiene

Chapter 7: Isolation of Communicable Diseases

Chapter 8: Patient Areas, Disinfection and Environmental Cleaning

Chapter 9: Reuse of Disposable Devices

Chapter 10: Disinfection

Chapter 11: The Healthcare Worker as a Source of Transmission

Chapter 12: Managing Antibiotic Resistance: What Works in the Hospital

Chapter 13: Organizing and Recording Problems Including Epidemics

Chapter 14: Horizontal vs Vertical Infection Control Strategies

Chapter 15: Positive Deviance in Infection Prevention

Chapter 16: Bundles in Infection Prevention and Safety

Chapter 17: The Hospital Environment

Chapter 18: Food: Considerations for Hospital Infection Control

Chapter 19: Hospital Water

Chapter 20: Laboratory Areas

Chapter 21: The Pharmacy

Chapter 22: The Operating Room

Chapter 23: Keeping the Environment Safe in Infection Prevention & Control: Focus on Countries with Limited Resources

Chapter 24: The Emergency Department and Receiving Areas

Chapter 25: HIV Infection and AIDS in Low- and Middle-Income Countries

Chapter 26: Tuberculosis

Chapter 27: Diarrhea

Chapter 28: Skin and Soft Tissue Infections

Chapter 29: Bloodstream Infections

Chapter 30: Managing Vascular Catheters

Chapter 31: Hospital Acquired Urinary Tract Infection

Chapter 32: Pneumonia

Chapter 33: Mechanical Ventilation

Chapter 34: Diphtheria, Tetanus, Pertussis

Chapter 35: Measles

Chapter 36: Herpes Zoster Vaccine

Chapter 37: Human Papillomavirus

Chapter 38: Transfusions

Chapter 39: Preparing the Patient for Surgery

Chapter 40: Infection Control in Obstetrics

Chapter 41: The Infection Hazards of Human Cadavers

Chapter 42: Streptococcus pyogenes (Group A Streptococcus Infections)

Chapter 43: Straphlococcus aureus

Chapter 44: Enterococcal Species

Chapter 45: Pneumococcus

Chapter 46: Legionella

Chapter 47: Carbapenem-resistant Enterobacteriaceae

Chapter 48: Bacterial Enteric Pathogens: Clostridium difficile, Salmonella, Campylobacter, Shigella, Escherichia Coli and others

Chapter 49: Other Enterobacteriaceae

Chapter 50: Pseudomonas Aeruginosa

Chapter 51: Helicobacter Pylori

Chapter 52: Fungi

Chapter 53: Viruses

Chapter 54: MERS and Lessons from SARS

Chapter 55: Parasites

Chapter 56: New Technologies in Infection Prevention

Chapter 57: Left Ventricular Assist Device - Related Infections

Chapter 58: Hand Hygiene Monitoring

Chapter 59: Healthcare Personnel Attire in Non-Operating Room Settings

Chapter 60: Ebola Virus Disease

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